Hydrogen Peroxide as a Potent Antimicrobial Agent in Contact Lens Care Solutions

Abstract

Assessing lens visibility in terms of transmittance is vital for those who wear contact lenses. To improve this visibility, various contact lens solutions are applied to disinfect the lenses effectively. Three bacterial strains sourced from contact lens storage cases were utilized to detect and characterize a biofilm. Three models were utilized, specifically, the biofilm model, the aging well plates model, and Planktonic model. Hydrogen peroxide is still the main contact solution that has an antimicrobial effect against different microbes. The effect of hydrogen peroxide was tested against three either in planktonic or biofilm formation strains, including Stenotrophomonas maltophilia (ALC-01), Elizabethkingia meningoseptica (3AS), and Achromobacter (AH-2A), along with Acanthamoeba castellanii 50370. It shows a higher effective contact lens solution compared with another common multipurpose contact lens solution. The hydrogen peroxide formulation shows significant disinfection potential and is compatible with multiple contact lens types, suggesting it could serve as a valuable option for improving lens hygiene and visibility