Evaluating the Anti-Inflammatory Potential of Reality Extra Compared to Conventional NSAIDs

Abstract

The critical response of the immune system to infections and tissue injuries, known as inflammation, is the foundational mechanism for various pathological conditions in human diseases. This inflammatory process is vital to ensure survival during adverse events. This study aimed to examine the anti-inflammatory effects of Reality Extra in vitro and compare its efficacy with those of ketoprofen and ibuprofen. Three drugs were used at concentrations of 5, 10, and 20 µg/ml, and the albumin denaturation method was used to elucidate their anti-inflammatory effects. Data were analyzed using a statistical software program (SPSS 26). In this study, we determined that Reality Extra exhibited higher anti-inflammatory activity than ketoprofen and ibuprofen. The IC₅₀ value of Reality Extra was 1.59 µg/ml, whereas the IC₅₀ values of ketoprofen and ibuprofen were 3.52 and 5.89 µg/ml, respectively. The findings of this study demonstrate that Reality Extra exhibits more pronounced anti-inflammatory effects than ketoprofen and ibuprofen. Additional studies are warranted to elucidate com-prehensive toxicity profiles